Annamaria Naggi Selected Research

roneparstat

1/2020	Novel N-acetyl-Glycol-split heparin biotin-conjugates endowed with anti-heparanase activity.
1/2017	Structural features of heparanase-inhibiting non-anticoagulant heparin derivative Roneparstat.
11/2016	Investigating Glycol-Split-Heparin-Derived Inhibitors of Heparanase: A Study of Synthetic Trisaccharides.

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Annamaria Naggi Research Topics

Disease

21	Neoplasms (Cancer) 02/2020 - 08/2002
12	Neoplasm Metastasis (Metastasis) 01/2018 - 04/2005
10	Inflammation (Inflammations) 01/2022 - 08/2002
5	Melanoma (Melanoma, Malignant) 01/2020 - 08/2002
3	Chronic Disease (Chronic Diseases) 01/2020 - 03/2014
3	Anemia 01/2020 - 03/2014
2	Hemorrhage 01/2022 - 05/2012
2	Thrombocytopenia (Thrombopenia) 01/2022 - 10/2017
2	Infections 01/2022 - 01/2018
2	Multiple Myeloma 01/2020 - 03/2011
2	Atherosclerosis 01/2020 - 08/2002
2	Human Influenza (Influenza) 07/2014 - 10/2013
1	Hypertension (High Blood Pressure) 01/2022
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Proteinuria 01/2022
1	Breast Neoplasms (Breast Cancer) 02/2020
1	Iron Overload 01/2020
1	Chondrosarcoma 12/2018
1	Multiple Hereditary Exostoses (Hereditary Multiple Exostoses) 12/2018
1	Persistent Infection 01/2018
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2018
1	Synovial Sarcoma (Synovioma) 01/2018
1	Cystic Fibrosis (Mucoviscidosis) 06/2016
1	Pain (Aches) 06/2016
1	Thrombosis (Thrombus) 11/2014
1	Virus Diseases (Viral Diseases) 07/2014
1	Experimental Melanoma 05/2014
1	Bone Resorption 01/2011
1	Abdominal Pain (Pain, Abdominal) 10/2009
1	Hypotension (Low Blood Pressure) 10/2009
1	Carcinoma (Carcinomatosis) 11/2007
1	Leukemia 01/2007
1	Wounds and Injuries (Trauma) 02/2005

Drug/Important Bio-Agent (IBA)

26	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 08/2002
15	heparanaseIBA 01/2020 - 02/2005
9	AnticoagulantsIBA 01/2022 - 07/2007
8	Heparitin Sulfate (Heparan Sulfate)IBA 12/2018 - 08/2002
5	Pharmaceutical PreparationsIBA 01/2022 - 01/2006
5	GlycosaminoglycansIBA 02/2020 - 08/2002
4	HepcidinsIBA 01/2020 - 03/2014
3	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2022 - 05/2014
3	roneparstatIBA 01/2020 - 11/2016
3	Proteins (Proteins, Gene)FDA Link 10/2017 - 08/2002
3	BorohydridesIBA 01/2017 - 03/2013
3	metaperiodate (periodate)IBA 01/2017 - 03/2013
3	Polysaccharides (Glycans)IBA 07/2014 - 07/2007
3	SelectinsIBA 05/2012 - 07/2007
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011 - 08/2002
3	EnzymesIBA 09/2007 - 01/2006
2	Syndecan-1 (Syndecan 1)IBA 01/2022 - 09/2007
2	P-SelectinIBA 02/2020 - 05/2014
2	GlucuronidaseIBA 01/2020 - 07/2007
2	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2018 - 07/2007
2	IronIBA 12/2014 - 03/2014
2	L-SelectinIBA 05/2014 - 11/2007
2	IntegrinsIBA 05/2014 - 05/2012
2	Integrin alpha4beta1 (VLA-4)IBA 05/2014 - 05/2012
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2011 - 02/2005
2	Glycoside Hydrolases (Endoglycosidases)IBA 11/2007 - 08/2002
2	Sulfates (Sulfates, Inorganic)IBA 09/2007 - 08/2002
1	CreatinineIBA 01/2022
1	Pentosan Sulfuric Polyester (Pentosan Polysulfate)FDA Link 01/2022
1	CholesterolIBA 01/2022
1	Fondaparinux (Arixtra)FDA Link 02/2020
1	Adenosine Triphosphate (ATP)IBA 02/2020
1	AvidinIBA 01/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	Drug CombinationsIBA 01/2018
1	Biotin (Vitamin H)FDA Link 01/2018
1	AntibodiesIBA 10/2017
1	Platelet Factor 4IBA 10/2017
1	Macromolecular SubstancesIBA 10/2017
1	Uronic AcidsIBA 11/2016
1	Antimalarials (Antimalarial Agents)IBA 06/2016
1	Peptide Hormones (Polypeptide Hormones)IBA 12/2014
1	Viral HemagglutininsIBA 07/2014
1	Tinzaparin (Innohep)FDA Link 05/2014
1	RNA (Ribonucleic Acid)IBA 05/2014
1	LipopolysaccharidesIBA 03/2014
1	SolutionsIBA 10/2013
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 05/2012
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2011
1	SST 0001IBA 03/2011
1	Messenger RNA (mRNA)IBA 01/2011
1	Carrier Proteins (Binding Protein)IBA 07/2010
1	OligosaccharidesIBA 07/2010
1	Cell Adhesion MoleculesIBA 11/2007
1	heparitinsulfate lyaseIBA 09/2007
1	Bacterial PolysaccharidesIBA 07/2007
1	adhesion receptorIBA 07/2007
1	Thromboplastin (Tissue Factor)IBA 01/2007

Therapy/Procedure

6	Therapeutics 01/2020 - 02/2005
1	Kidney Transplantation 01/2022
1	Transplantation 01/2022
1	Drug Therapy (Chemotherapy) 01/2018
1	Injections 03/2014